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Latest NewsCMS Releases List of 15 Drugs for MDPNP Effective 2028 The Centers for Medicare & Medicaid Services (CMS) announced the selection of 15 high-cost prescription drugs covered under Medicare Part D and, for the first time, drugs payable under Medicare Part B for the third cycle of the Medicare Drug Price Negotiation Program (MDPNP). CMS also selected one previously negotiated drug for the program’s first renegotiations. Negotiations with participating drug companies will occur in 2026 and any negotiated and renegotiated prices will become effective January 1, 2028. The selected drug list for the third cycle of negotiations is: Anoro Ellipta; Biktarvy; Botox/Botox Cosmetic; Cimzia; Cosentyx; Entyvio; Erleada; Kisqali; Lenvima; Orencia; Rexulti; Trulicity; Verzenio; Xeljanz/Xeljanz XR; and Xolair. The selected drug for renegotiation is Tradjenta. See here for a fact sheet on the drugs selected for negotiation and renegotiation. CMS has also released a list of 50 top negotiation-eligible drugs based on combined expenditures under Medicare Parts B and D. The drugs selected for the third cycle represent the top 15 highest-spending drugs on this list.
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